INVEGA HAFYERA® is the only medication that treats schizophrenia with 1 dose every 6 months.
Since shifting to being treated with INVEGA HAFYERA®, my life is less defined by schizophrenia medication, and I now experience 6 months of symptom control with each dose.
– A schizophrenia community member
INVEGA HAFYERA® is different from both INVEGA SUSTENNA® and INVEGA TRINZA®, in that it's an injection given twice a year, every 6 months.
Your healthcare professional will start treatment for your schizophrenia with INVEGA SUSTENNA®, the once-monthly version of the active medication in INVEGA HAFYERA®. You need to be on INVEGA SUSTENNA® for at least 4 months with the last 2 doses being 156 mg or 234 mg. Then you can transition to INVEGA TRINZA® after being adequately treated for at least 4 months, or you can transition to INVEGA HAFYERA®.
If you and your healthcare professional decide that you should transition to INVEGA TRINZA® before starting on INVEGA HAFYERA®, you will need to be adequately treated with INVEGA TRINZA® for one 3-month cycle (one dose of 546 mg or 819 mg).
It's important to be patient, because starting any new medication can be challenging. Work with your healthcare professional to find the right dose of INVEGA HAFYERA® that will help control schizophrenia symptoms with the fewest side effects.It's very important that you go to all of your injection appointments. If you miss an injection, talk to your treatment team as soon as possible. If you are experiencing symptoms or side effects, be sure to let your healthcare professional know. You and your treatment team members can also discuss options to help remember your injection appointments, or if you might be able to receive your injection at a place near you other than your healthcare professional's office.
A long-term, global clinical study was conducted to show whether INVEGA HAFYERA® was as effective as (noninferiority) INVEGA TRINZA® in symptom control with similar safety and side effects.
In this study, 92.5% of patients treated with INVEGA HAFYERA® and 95% of patients treated with INVEGA TRINZA® did not experience an episode at 12 months.
The most common side effects of INVEGA HAFYERA® include:
INVEGA HAFYERA® is to be used after adequate treatment with either INVEGA SUSTENA® for at least 4 months or INVEGA TRINZA® following at least one 3-month injection cycle at an appropriate dose.
Patients who were relapse-free after 1 year in the noninferiority study were eligible to continue in this study.
96.1% of patients taking INVEGA HAFYERA® were relapse-free.
87% of patients completed 2 years of treatment with INVEGA HAFYERA® in a real-world, open-label extension study.
Learn about a path to a twice-yearly treatment with INVEGA HAFYERA®.